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作者:2023-03-04 00:00 点赞 收藏 热度:14

1、单选题:
Which of the following drugs is an inducer of CYP1A2 ( )
选项:
A:Fluconazole
B:Simvastatin
C:Tobacco
D:Ciprofloxacin
答案: 【Tobacco

2、单选题:
The process of renal excretion of drugs does not include which of the following options ( )
选项:
A:Hepatoenteric circulation
B:Glomerular filtration
C:Active secretion of renal tubules
D:passive tubule reabsorption
答案: 【Hepatoenteric circulation

3、单选题:
Which of the following statements is false ( )
选项:
A:Tmax refers to the time that takes a drug or other substance to reach the maximum concentration Cmax
B:T half (T1/2)of a drug refers to the time required for the plasma concentration of the drug to drop by half
C:AUC refers to Area under the curve (pharmacokinetics), regarding plasma drug concentration-time curves
D:The time required to reach half of Cmax by oral administration is different from the time required for half of Cmax intravenously
答案: 【The time required to reach half of Cmax by oral administration is different from the time required for half of Cmax intravenously

4、多选题:
The main factors affecting drug absorption are ( )
选项:
A:The first pass effect
B:pH value
C:Blood flow
D:Administration route
答案: 【The first pass effect;
pH value;
Blood flow;
Administration route

5、单选题:
The bioavailability of the drug refers to ( )
选项:
A:The fraction or percentage of a drug that reaches hepatic portal circulation
B:The relative speed of the drug absorption into the body
C:The fraction or percentage of a drug that reaches systemic circulation
D:The fraction or percentage of a drug that reaches the action point
答案: 【The fraction or percentage of a drug that reaches systemic circulation

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